Cancer Chemoprevention (e-bok)
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Humana Press
Cancer Chemoprevention (e-bok)

Cancer Chemoprevention E-bok

Volume 1: Promising Cancer Chemopreventive Agents

E-bok (PDF - DRM), Engelska, 2004-06-04
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These two volumes provide a comprehensive survey of promising cancer chemopreventive agents, grouped by pharmacological and or mechanistic classes. The agent classes vary widely in terms of their stage of development as chemopreventatives, ranging from extensively covered groups such as nonsteroidal anti-inflamatories and anti-estrogens to drugs with recently identified potential based on mechanistic data such as protein kinase inhibitors.
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Part I. Antimutagens; 1 Inducers of Enzymes that Protect against Carcinogens and Oxidants: Drug and Food Based Approaches with Dithiolethiones and Sulforaphane Thomas W. Kensler and Paul Talalay; 2 Chemoprevention by Isothiocyanates Stephen S. Hecht; 3 Antigenotoxic and Cancer Preventive Mechanisms of N-Acetyl-L-Cysteine Silvio De Flora, Alberto Izzotti, Adriana Albini, Francesco D'Agostini, Maria Bagnasco, and Roumen Balansky; 4 Modifiers of P450 Cytochrome(s) John DiGiovanni and Heather E. Kleiner; Part II. Anti-Inflammatories; 5 Anti-Inflammatories and Chemoprevention: NSAIDs and Other Inhibitors of Arachidonic Acid Metabolism Gary B. Gordon, Gary J. Kelloff, and Caroline C. Sigman; 6 Cyclooxygenase-2 Inhibitors and Colorectal Cancer Prevention Raymond N. DuBois; 7 Lipoxygenases as Targets for Cancer Prevention Susan M. Fischer and Russell D. Klein; 8 Inducible Nitric Oxide Synthase as a Target for Chemoprevention Lorne J. Hofseth, Tomohiro Sawa, S. Perwez Hussain, and Curtis C. Harris; 9 Chemoprevention of Cancer of the Respiratory Tract by Agents Delivered by Aerosol: Applications to Glucocorticoids and 5-Fluorouracil Timothy S. Wiedmann and Lee W. Wattenberg; 10 Chemoprevention of Cancer by Curcumin Bandaru S. Reddy and Chinthalapally V. Rao; 11 Prostacyclin and Lung Cancer Chemoprevention Robert L. Keith, York E. Miller, Paul A. Bunn, Jr, Patrick Nana-Sinkam, Raphael A. Nemenoff, and Mark W. Geraci; Part III. Nuclear Receptor Superfamily; 12 Nuclear Receptor Superfamily: Targets for Chemoprevention Julia Lawrence and Kapil Dhingra; A. Antiandrogens; 13 Prostate Cancer Chemoprevention: 5-[alpha] Reductase Inhibitors Jennifer E. Drisko and Siu-Long Yao; 14 Searching for SARA: The Role of Selective Androgen Receptor Antagonists in Prostate Cancer Mark S. Chapman, William Y. Chang, Andres Negro-Vilar, and Jeffrey N. Miner; B. Antiestrogens; 15 Aromatase Inhibitors as Chemopreventives of Breast Cancer Mitchell Dowsett and Judy E. Garber; 16 Breast Cancer Chemoprevention by Selective Estrogen Receptor Modulators Carolyn L. Smith; C. Natural Vitamin D and Synthetic Analogs; 17 Chemopreventive Efficacy of Natural Vitamin D and Synthetic Analogs Kathryn Z. Guyton, Thomas W. Kensler, and Gary H. Posner; D. Retinoids; 18 The Retinoids and Cancer Chemoprevention Sutisak Kitareewan, Ian Pitha-Rowe, Yan Ma, Sarah J. Freemantle, and Ethan Dmitrovsky; E. Dehydroepiandrosterone and Structural Analogs; 19 Biologic and Therapeutic Effects of Dehydroepiandrosterone and Structural Analogs Arthur G. Schwartz and Laura L. Pashko; Part IV. Signal Transduction Modulators; 20 Ras Oncogene Inhibitors Nancy E. Kohl; 21 The Potential of EGFR-targeted Agents in Cancer Prevention Steven D. Averbuch and Fadlo R. Khuri; 22 Pharmacological Intervention with Multistep Oncogenesis: Potential Role for HSP90 Molecular Chaperone Inhibitors Paul Workman; 23 Therapeutic Strategies Targeting Polyamines Debora L. Kramer and Eugene W. Gerner; 24 The Role of Phytoestrogens as Cancer Prevention Agents Stephen Barnes and Coral A. Lamartiniere; 25 Cancer Chemopreventive Activity of Monoterpenes and Other Isoprenoids Pamela L. Crowell and Michael N. Gould