Cancer Chemoprevention E-bok

Part I. Antimutagens; 1 Inducers of Enzymes that Protect against Carcinogens and Oxidants: Drug and Food Based Approaches with Dithiolethiones and Sulforaphane Thomas W. Kensler and Paul Talalay; 2 Chemoprevention by Isothiocyanates Stephen S. Hecht; 3 Antigenotoxic and Cancer Preventive Mechanisms of N-Acetyl-L-Cysteine Silvio De Flora, Alberto Izzotti, Adriana Albini, Francesco D'Agostini, Maria Bagnasco, and Roumen Balansky; 4 Modifiers of P450 Cytochrome(s) John DiGiovanni and Heather E. Kleiner; Part II. Anti-Inflammatories; 5 Anti-Inflammatories and Chemoprevention: NSAIDs and Other Inhibitors of Arachidonic Acid Metabolism Gary B. Gordon, Gary J. Kelloff, and Caroline C. Sigman; 6 Cyclooxygenase-2 Inhibitors and Colorectal Cancer Prevention Raymond N. DuBois; 7 Lipoxygenases as Targets for Cancer Prevention Susan M. Fischer and Russell D. Klein; 8 Inducible Nitric Oxide Synthase as a Target for Chemoprevention Lorne J. Hofseth, Tomohiro Sawa, S. Perwez Hussain, and Curtis C. Harris; 9 Chemoprevention of Cancer of the Respiratory Tract by Agents Delivered by Aerosol: Applications to Glucocorticoids and 5-Fluorouracil Timothy S. Wiedmann and Lee W. Wattenberg; 10 Chemoprevention of Cancer by Curcumin Bandaru S. Reddy and Chinthalapally V. Rao; 11 Prostacyclin and Lung Cancer Chemoprevention Robert L. Keith, York E. Miller, Paul A. Bunn, Jr, Patrick Nana-Sinkam, Raphael A. Nemenoff, and Mark W. Geraci; Part III. Nuclear Receptor Superfamily; 12 Nuclear Receptor Superfamily: Targets for Chemoprevention Julia Lawrence and Kapil Dhingra; A. Antiandrogens; 13 Prostate Cancer Chemoprevention: 5-[alpha] Reductase Inhibitors Jennifer E. Drisko and Siu-Long Yao; 14 Searching for SARA: The Role of Selective Androgen Receptor Antagonists in Prostate Cancer Mark S. Chapman, William Y. Chang, Andres Negro-Vilar, and Jeffrey N. Miner; B. Antiestrogens; 15 Aromatase Inhibitors as Chemopreventives of Breast Cancer Mitchell Dowsett and Judy E. Garber; 16 Breast Cancer Chemoprevention by Selective Estrogen Receptor Modulators Carolyn L. Smith; C. Natural Vitamin D and Synthetic Analogs; 17 Chemopreventive Efficacy of Natural Vitamin D and Synthetic Analogs Kathryn Z. Guyton, Thomas W. Kensler, and Gary H. Posner; D. Retinoids; 18 The Retinoids and Cancer Chemoprevention Sutisak Kitareewan, Ian Pitha-Rowe, Yan Ma, Sarah J. Freemantle, and Ethan Dmitrovsky; E. Dehydroepiandrosterone and Structural Analogs; 19 Biologic and Therapeutic Effects of Dehydroepiandrosterone and Structural Analogs Arthur G. Schwartz and Laura L. Pashko; Part IV. Signal Transduction Modulators; 20 Ras Oncogene Inhibitors Nancy E. Kohl; 21 The Potential of EGFR-targeted Agents in Cancer Prevention Steven D. Averbuch and Fadlo R. Khuri; 22 Pharmacological Intervention with Multistep Oncogenesis: Potential Role for HSP90 Molecular Chaperone Inhibitors Paul Workman; 23 Therapeutic Strategies Targeting Polyamines Debora L. Kramer and Eugene W. Gerner; 24 The Role of Phytoestrogens as Cancer Prevention Agents Stephen Barnes and Coral A. Lamartiniere; 25 Cancer Chemopreventive Activity of Monoterpenes and Other Isoprenoids Pamela L. Crowell and Michael N. Gould