An Introduction to Genetic Epidemiology

"This book should be incredibly useful to students and researchers at all levels in genetic epidemiology. For students it offers an eminently readable and accessible foundation, and for researchers, a superb source to fill in missing pieces in our knowledge." Ezra Susser, Professor of Epidemiology and Psychiatry, Mailman School of Public Health, Columbia University, and New York State Psychiatric Institute. "This is a sobering must-read for anyone who wishes to know how genetic epidemiology may change how we understand, treat or prevent human disease." Robert Elston, Case Western Reserve University School of Medicine

Lyle Palmer is the Foundation Chair in Genetic Epidemiology and founding Director of the Centre for Genetic Epidemiology and Biostatistics at the University of Western Australia, where he is also a Professor in the Schools of Medicine & Pharmacology and Population Health. Paul Burton is Professor of Genetic Epidemiology at the University of Leicester. George Davey Smith is Professor of Clinical Epidemiology at the University of Bristol.

Key concepts in genetic epidemiology ~ Paul R Burton, Martin D Tobin and John L Hopper; Genetic linkage studies ~ M Dawn Teare and Jennifer H. Barrett; Genetic association studies ~ Heather J. Cordell and David G. Clayton; Mapping complex disease genes using linkage disequilibrium and genome-wide association scans ~ Lyle J Palmer, Nicholas J Timpson, David M Evans, George Davey Smith and Lon R Cardon; A question of standards: what makes a good genetic association study? ~ Andrew T Hattersley and Mark I McCarthy; Biobanks and biobank harmonisation ~ Paul R Burton, Isabel Fortier, Mylene Deschenes, Anna Hansell and Lyle J Palmer; Population health aspects of genetic epidemiology: genomic profiling, personalised medicine, and Mendelian randomisation ~ George Davey Smith, Shah Ebrahim, Sarah Lewis and Lyle J Palmer.