Brain Edema XII (inbunden)
Inbunden (Hardback)
Antal sidor
2003 ed.
Springer Verlag GmbH
Kuroiwa, T. (ed.), Baethmann, A. (ed.), Czernicki, Z. (ed.), Hoff, J. T. (ed.), Ito, U. (ed.), Katayama, Y. (ed.), Marmarou, A. (ed.), Mendelow, D. (ed.), Reulen, H. -J. (ed.)
XV, 612 p.
PREL 100: v.12
283 x 217 x 29 mm
1852 g
Antal komponenter
1 Hardback
Brain Edema XII (inbunden)

Brain Edema XII

Proceedings of the 12th International Symposium, Hakone, Japan, November 10-13, 2002

Inbunden Engelska, 2003-12-01
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Brain edema is a simple phenomenon - an abnormal increase of brain tissue volume by the increase of brain tissue water content. However the etiology is not simple and relating to a wide variety of neurological disorders including ischemia, trauma, tumor, hemorrhage and hydrocephalus. It is still a major cause of death in the neurological/neurosurgical ward. This volume is an up-to-date report on progress in brain edema research, diagnosis and treatment, including papers presented at the 12th International Symposium on Brain Edema and Brain Tissue Injury in 2002. Major topics include molecular biology and blood-brain barrier disorders, ischemic and traumatic brain edema, imaging and diagnosis of brain edema, treatment and radiation effect. Various papers in the rapidly growing fields of neuroimaging and molecular medicine are also included.
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General review.- Concept and pathogenesis of "hypoxic-ischemic encephalopathy".- Pathophysiology of traumatic brain edema : current concepts.- Brain edema from intracerebral hemorrhage.- Hydrostatic brain edema: basic mechanisms and clinical aspect.- Non-invasive imaging methods for the characterization of the pathophysiology of brain ischemia.- Cecile & Oskar Vogt: The significance of their contributions in modern neuroscience.- Imaging.- Estimating blood-brain barrier opening in a rat model of hemorrhagic transformation with Patlak plots of Gd-DTPA contrast-enhanced MRI.- Recent development of MR imaging technique for the investigation of brain function.- Energy metabolism and cerebral blood flow during cytotoxic brain edema induced by 6-aminonicotinamide.- PET neuroreceptor imaging as predictor of severe cerebral ischemic insult.- Pet investigation of post-traumatic cerebral blood volume and blood flow.- Quantitative evaluation of cerebral vascular permeability using multi-slice dynamic CT.- Acetazolamide vasoreactivity evaluated by transcranial harmonic perfusion imaging: relationship with transcranial Doppler sonography and dynamic CT.- Functional brain imaging of optical topography.- Experimental global ischemia.- Significant shrinkage of extracellular space during global cerebral ischemia: differences in gray and white matter ischemia.- NTP and PCr responses to hypoxia by hypothermic and normothermic respiring, superfused, neonatal rat cerebrocortical slices: an NMR spectroscopy study at 14.1 Tesla.- Matrix metalloproteinases are not involved in early brain edema formation after cardiac arrest in rats.- Regional N-acetyl-aspartate level and immunohistochemical damage in the hippocampus after transient forebrain ischemia in gerbils.- Extracellular superoxide dismutase following cerebral ischemia in mice.- Peroxynitrite and caspase-3 expression after ischemia/reperfusion in mouse cardiac arrest model.- Expression oftumor necrosis factor ? (TNF?) following transient cerebral ischemia.- Evaluation of neuronal cell death after a new global ischemia model in infant mice.- Hippocampal heme oxigenase-1 in a murine cardiac arrest model.- Calcineurin and cyclophilin D are differential targets of neuroprotection by immunosuppressants CsA and FK506 in ischemic brain damage.- FK506 attenuates the post-ischemic perturbation of protein kinases and tyrosine phosphorylation in the gerbil hippocampal CA1 sectors.- Blood-brain barrier dysfunction and amyloid precursor protein accumulation in microvascular compartment following ischemia-reperfusion brain injury with 1-year survival.- Neuroprotective effect from ischemia and direct free radical scavenging activity of Choto-san (kampo medicine).- Experimental focal ischemia.- Temporal profile of experimental ischemic edema after threshold amount of insult to induce infarction-ultrastructure, gravimetry and Evans' blue extravasation.- Prediction of tissue survival after stroke based on changes in the apparent diffusion of water (cytotoxic edema).- Recovery of apparent diffusion coefficient after embolic stroke does not signify complete salvage of post-ischemic neuronal tissue.- Temporal evolution of apparent diffusion coefficient and T2 value following transient focal cerebral ischemia in gerbils.- Prediction of malignant infarction: perifocal neurochemical monitoring following prolonged MCA occlusion in cats.- A comparison of long-term neurological symptoms after two different focal ischemic models in Mongolian gerbils.- Thrombin exacerbates brain edema in focal cerebral ischemia.- Infiltration of tissue plasminogen activator through cerebral vessels: evaluation using a rat thromboembolic stroke model.- Mice deficient in cytosolic phospholipase A2 are less susceptible to cerebral ischemia/reperfusion injury.- Regional distribution of potassium and phosphorus in ischemic brain tissue of rats with X-ray fluorescence analysis.- Changes of free cholesterol and neutrallipids after t