An introduction to synovial joints; the development of joints and articular cartilage; the role of hyaluronan in joint cavitation; articular cartilage morphology and biology; the collagens of articular and meniscal cartilages; collagens in joint tissues; matrix turnover in joint tissues - the role of metalloproteinases; the biology of synovial cells; the biochemistry of the synovium and synovial fluid; ageing and pathology of the rotator cuff; the attachment of tendons and ligaments to bone; principles of joint biomechanics; clinical problems associated with the hand and forearm.