Proteiner

With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. Details cutting-edge ADME (absorption, distribution, meta...

Läs mer »

Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy. In this first volume on Drug Transporters, the current knowledge and techniques in the transporter ...

Läs mer »

Active, accessible, and assuming no prior knowledge: the ideal text for biologists encountering bioinformatics for the first time.

Läs mer »

Exploring Proteins offers a complete course in developing the skills to be able to understand the way proteins behave and the methods used to separate, identify and characterise them. It equips you with the skills you need to plan and carry out th...

Läs mer »

This book provides a comprehensive coverage of the basic principles of structural biology, as well as an up-to-date summary of some main directions of research in the field. The relationship between structure and function is described in detail fo...

Läs mer »

This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regul...

Läs mer »

Proteins in Food Processing, Second Edition, reviews how proteins may be used to enhance the nutritional, textural and other qualities of food products. After two introductory chapters, the book discusses sources of proteins, examining the caseins...

Läs mer »

Immunosensing for Detection of Protein Biomarkers not only introduces the principles, methods, and classification of immunoassay, but also presents the latest achievements in areas such as electrochemical immunosensors, nanoprobe-based immunoassay...

Läs mer »

From Globular Proteins to Amyloids proposes a model and mechanism for explaining protein misfolding. Concepts presented are based on a model originally intended to show how proteins attain their native conformations. This model is quantitative in ...

Läs mer »

From the Reviews of the Previous Volumes "The authority, originality, and editing of the reviews are first class." -NATURE "The Advances in Protein Chemistry series has been a major factor in the education of protein chemists." -JOURNAL OF THE AME...

Läs mer »

Praise for the Series: "The authority, originality, and editing of the review are first class." --Nature "The Advances in Protein Chemistry series has been a major factor in the education of protein chemists." --Journal of the American Chemical So...

Läs mer »

This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-th...

Läs mer »

A cofactor is a component part of many enzymes and functions by uniting with another molecule in order to become active. The use of cofactors to supplement the native amino acids of a protein is essential to maintain the chemical capabilities nece...

Läs mer »

A wide range of researchers are currently investigating different properties and applications for copper-containing proteins. Biochemists researching metal metabolism in organisms ranging from bacteria to plants to animals are working in a complet...

Läs mer »

Protein Transcription is a key element of cellular and organ regulation. Proteins in Eukaryotic Transcription covers structure and function of all major elements associated with transcription. Mechanism of RNA polymerase I Transcription Structure ...

Läs mer »

Volume 72, Peptide Solvation and H-bonds , addresses the role of peptide backbone solvation in the energetics of protein folding. Particular attention is focused on modeling and computation. This volume will be of particular interest to biophysici...

Läs mer »

Hubert Rehm's Protein Biochemistry and Proteomics is more than a laboratory manual; it is a strategic guide that provides the reader with tips and tricks for more successful lab experiments. Using a conversational yet professional tone, Rehm provi...

Läs mer »

This is the first compilation of protein lipidation enzymes. This volume summarizes recent dramatic developments regarding enzymes responsible for protein lipidation, a process critical for a number of physiological functions, including cell proli...

Läs mer »

The design and production of novel peptides and proteins occupy pivotal positions in science and technology and will continue to do so in the 21st century. Protein Engineering and Design outlines the rapid advances in computer-based modeling, prot...

Läs mer »

Integrins: Molecular and Biological Responses to the Extracellular Matrix will help basic, applied, and clinical researchers keep up with the explosion of literature on the integrin family of proteins. This volume extends material previously cover...

Läs mer »

Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein folding and ligand-acceptor interactions are included in Volumes 202 and 203, as are genetic and chemical method...

Läs mer »

Methods widely used in the study of DNA binding proteins are presented in this volume. These include purification and protein characterization, assays of protein-DNA binding and protein-induced bending, and biochemical and genetic methods for prob...

Läs mer »

This volume of Methods in Enzymology and its companion Volume 238 include molecular, biological, and biochemical methods for the study of cell surface heterotrimeric G proteins (Volume 237) and their effectors (Volume 238). Methods unique to signa...

Läs mer »

General Description of the Volume: The role of low molecular weight cofactors (often vitamins) in enzyme catalysis has been discussed in many earlier volumes of Methods in Enzymology . Exciting new results indicate that redox-active prosthetic gro...

Läs mer »

Ubiquitin and Protein Degradation, Part B covers chemical biology, ubiquitin derivatives and ubiquitin-like proteins, deubiquitinating enzymes, proteomics as well as techniques to monitor protein degradation. The chapters are highly methodological...

Läs mer »

The Ras superfamily (150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl...

Läs mer »

The Ras superfamily (150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl...

Läs mer »

The Academic Press FactsBooks series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as 'a growing series of excellent manuals' by Molecular Medicine Today , and 'essential works of...

Läs mer »

This book describes the complex structures of heparins and heparan sulfates (heparinoids) and how they are generated by their biosynthetic pathways. The book also details the methodologies for studying these structures and their cellular metabolis...

Läs mer »